Which medication treats hay fever by preventing leukotriene synthesis?

Zileuton is the medication that treats hay fever by preventing leukotriene synthesis. Leukotrienes are inflammatory mediators that play a significant role in allergic reactions and asthma. By inhibiting their synthesis, Zileuton helps to reduce inflammation and alleviate symptoms associated with conditions like hay fever.

This mechanism distinguishes Zileuton from other options. Cromolyn sodium, for example, works by stabilizing mast cells and preventing the release of histamine and other inflammatory mediators, rather than blocking leukotriene synthesis. Chlorpheniramine and diphenhydramine are both antihistamines; they work by antagonizing histamine receptor activity to alleviate symptoms like sneezing and runny nose but do not specifically target leukotriene production or action. This unique mechanism of action makes Zileuton particularly effective in managing allergic responses linked to leukotrienes.